Week 3 Preview: Kyle Shanahan to test limits of running-backs-don't-matter movement

Kyle Shanahan built the 49ers around the ground game. But with his top four rushers in danger of missing Sunday's tilt with the Packers, he will test the limits of running-back fungibility.

The San Francisco 49ers will look significantly different Sunday than they did last November during their last encounter with the Green Bay Packers. The injuries and COVID-19 absences that thinned the 49ers' roster past the breaking point will feature all its biggest names, from Nick Bosa on defense to Jimmy Garoppolo and George Kittle on offense. None …